Decoding the Genes Behind Dolastatin 10 Paves the Way for New Cancer Therapeutics
Researchers at the University of Florida College of Pharmacy have identified the genes responsible for the creation of dolastatin 10, a marine natural product that has led to six FDA-approved cancer drugs since 2011. The research team used genomic library screening and genome sequencing to identify the genes responsible for producing the marine natural product.
Leveraging the Biodiversity of the Ocean to Discover New Cancer Treatments
From cyanobacterial blooms found off Florida’s Atlantic coast, Dr. Hendrik Luesch and his team of researchers have discovered a novel marine natural product named Gatorbulin-1 that binds to a new site on tubulin, an important target for cancer drugs.
UF Researchers Say Marine Products Show Promising Future In Medical Advancements
Many drug research efforts occurring at UF are focused on marine and natural products that will lead to advancements in medications and treatments for cancers. Dr. Hendrik Luesch was involved in a recent discovery of a marine compound off the east coast of Florida named gatorbulin-1 that could potentially be used in the fight against cancer; this discovery highlights the importance of searching the ocean’s biodiversity.
UF Researchers Discover Marine Natural Product off Florida’s Coast That Could Help Fight Cancer
University of Florida researchers have discovered a novel marine natural product that binds to a new site of tubulin, an important target for cancer drugs.
Eating Seaweed Could Prevent Colon Cancer, Inflammation of Digestive Tract, Study Suggests
Eating seaweed that grows near the Florida Keys could protect against colon cancer and inflammatory diseases of the digestive tract, according to... Read More
Novel Drug Inspired by a Marine Natural Product Offers New Approach to Treat Pancreatic Cancer (UF Health)
A novel drug candidate based on a marine natural product discovered 20 years ago could be the basis for a new approach... Read More
