Silver Nanoparticles Show Promise in Fighting Antibiotic-Resistant Bacteria

Silver Nanoparticles Show Promise in Fighting Antibiotic-Resistant Bacteria

A single E. coli bacteria cell surrounded by silver nanoparticles. Photo courtesy of Garrett Ellward.

In a new study, scientists with the University of Florida found that a combination of silver nanoparticles and antibiotics was effective against antibiotic-resistant bacteria.

The researchers hope to turn this discovery into viable treatment for some types of antibiotic-resistant infections. Antibiotic-resistant infections kill more than a million people globally each year.

For centuries, silver has been known to have antimicrobial properties. However, silver nanoparticles — microscopic spheres of silver small enough to operate at the cellular level — represent a new frontier in using the precious metal to fight bacteria.

In this study, the research team tested whether commercially available silver nanoparticles boost the power of antibiotics and enable these drugs to counter the very bacteria that have evolved to withstand them.

“We found that the silver nanoparticles and a common class of broad-spectrum antibiotics called aminoglycosides work together synergistically,” said Daniel Czyz, senior author of the study and an assistant professor in the UF/IFAS department of microbiology and cell science.

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