Targeting RNA
Disney and his team at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology in Jupiter, Florida, have discovered more than 200 unique RNA-targeting compounds. His methods and discoveries have changed minds, igniting a global race to treat incurable diseases via their RNA.
UF Researchers’ Genetic Detection Discovery Has Implications for Medical Diagnostic Testing
University of Florida researchers have found a new use for “genetic scissors” to detect RNA, a discovery that could lead to faster, more accurate and less expensive diagnostic tests for a host of diseases.
Genetic Cause of Als and Dementia Repaired by RNA-Targeting Strategy Developed at UF Scripps
Scientists at UF Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The compound restored the health of neurons in the lab and rescued mice with the disease.
UF Scripps Researcher’s Drug-Discovery Method Shows Promise Against Aggressive Breast Cancer
UF Scripps Biomedical Research scientist Matthew Disney, Ph.D. has found yet another groundbreaking approach to a problem that has long vexed scientists: How to cure diseases by targeting key RNA. Until now, RNA has been an elusive target for drug discovery. Discoveries made by Disney and his collaborators have rewritten that dogma.