Novel Compound Offers Improved Defense Against Fentanyl Overdoses

Scientists at the University of Florida have identified a novel compound aimed at improving the treatment of opioid overdoses, which claimed the lives of more than 81,000 Americans last year.

The discovery could combat the devastating epidemic of opioid-related deaths, driven predominantly by the proliferation of fentanyl. The highly potent synthetic opioid is a pain reliever and among the nation’s most abused substances.

“Fentanyl is driving the need to find better treatments for opioid overdoses,” said Jay McLaughlin, Ph.D., a professor of pharmacodynamics in the UF College of Pharmacy. “Every opioid death is preventable, highlighting the immediate need to improve the treatment options.”

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