First Patient Enrolled in Rise Therapeutics’ Rheumatoid Arthritis Clinical Trial

Rise Therapeutics, a UF startup and a clinical-stage biotechnology company developing novel oral immunotherapeutic medicines, announced it has enrolled its first patient in its R-2487 Phase 1 rheumatoid arthritis clinical trial.

“This is an important milestone for the company and patients suffering from rheumatoid arthritis” states Gary Fanger president and chief executive officer of Rise Therapeutics. “This achievement reinforces our commitment to deliver innovative new medicines to the clinical community.”

Rheumatoid arthritis is a chronic, systemic inflammatory disorder affecting up to 0.24% of the world population, and as much as 1% of the US population. The exact frequencies depend on geographical origin and gender with women being three times more affected than men. Rheumatoid arthritis attacks the synovial joints of patients, where approximately half of the affected patients become disabled over the progression of the disease.

The Phase I rheumatoid arthritis clinical trial (NCT05961592) is a first-in-human clinical trial designed to understand safety, pharmacodynamics, and clinical activity of R-2487 in patients suffering from rheumatoid arthritis.

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