“Cuddle hormone” oxytocin may provide pain relief and help curb harmful opioid use

A two-year interdisciplinary study at UF examines synthetic oxytocin’s potential as an alternate pain management option for older adults.

In the midst of America’s growing opioid crisis, a much healthier alternative to long-term pain management is emerging — one affectionately known as “the cuddle hormone,” or oxytocin.

University of Florida researchers are investigating whether a synthetic version of this naturally occurring human hormone can be used in conjunction with prescription drugs to help curb opioid addictions, especially in susceptible older adults. An interdisciplinary research team is conducting the two-year study, with $414,375 in funding from the National Institutes of Health, and completion is expected in April 2025.

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