UF-Led Researchers Link New Genetic Mutation to Increased Risk of Parkinson’s

New research by a University of Florida-led international team has revealed evidence linking a new genetic mutation to greater risk of developing Parkinson’s disease.

The finding of the RAB32 Ser71Arg variant, reported April 10 in The Lancet Neurology is the latest advance by UF neurogeneticist Matthew J. Farrer, Ph.D., senior author of the new paper, whose lab has made past key discoveries involving genetic mutations that can cause Parkinson’s.

The new discovery unites the biology of several major genes for Parkinson’s disease, Farrer said. This knowledge will help scientists focus studies aimed at developing new medications to slow or halt progression of the disease.

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