Nci Grant Funds Study of Cancer Cachexia

Sarah Judge, Ph.D., a research assistant professor in the University of Florida College of Public Health and Health Professions, has received a $2.4 million, five-year grant from the National Cancer Institute to study the role of a key protein in driving cancer cachexia.

Cancer cachexia, which is highly prevalent in cancers of the pancreas and gastrointestinal tract, is a frequent complication of cancer involving muscle wasting and weakness. The breakdown of muscle tissue reduces patients’ physical function and worsens their quality of life. It also often negatively impacts their ability to withstand aggressive conventional cancer treatments and contributes to decreased survival. There are no known effective therapies to preserve or reverse the loss of muscle mass in patients with cancer.

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