UF Researchers Create Method To Predict Leukemia Drug Complications

A team of University of Florida researchers has created a way to use genetics to predict leukemia patients’ risk for complications from chemotherapy drug toxicity.

The team, led by UF Inventor Jatinder Lamba, Ph.D., associate dean of research and graduate education and a professor in the UF College of Pharmacy, made a comprehensive pharmacogenomics evaluation of key genes involved in the pathways of several commonly used drugs to treat acute lymphoblastic leukemia, or ALL, the most common type of leukemia in children. The study, which assessed toxicity data and DNA samples from 75 patients treated at UF Health, was published March 23 in the journal JCO Precision Oncology.

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