Assistant Professor Develops a Rapid Point-of-Care Detection Technology for SARS-Cov-2

Piyush Jain, Ph.D., an assistant professor in the Department of Chemical Engineering and a member of UF Health Cancer Center, and his Ph.D. student Long Nguyen have developed a CRISPR-based, paper-based, rapid detection technology that can detect SARS-CoV-2 cDNA in as little as 5-10 minutes or SARS-CoV-2 RNA in as low as 30-60 minutes without the need of expensive equipment. The technology combines a reverse transcription, an isothermal DNA amplification system with an engineered CRISPR/Cas-system, and a sensitive paper-based lateral flow assay.

They want to utilize this technology to create an inexpensive at-home Coronavirus test kit, similar to pregnancy test strips.

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