A team of researchers has verified that it is possible to engineer two-layered nanofibers consisting of an ordered row of alternating peptides, and has also determined what makes these peptides automatically assemble into this pattern. The fundamental discovery raises the possibility of creating a tailored “ABAB” peptide nanofibers with a variety of biomedical applications.
The study itself involved three components. Greg Hudalla’s lab at the University of Florida created the peptides, facilitated the co-assembly of the peptide beta sheets and performed experimental work that provided an overview of the system and its behavior. Hudalla co-authored the paper and is an associate professor in UF’s J. Crayton Pruitt Family Department of Biomedical Engineering.Learn more about Researchers Show What Drives a Novel, Ordered Assembly of Alternating Peptides.