UF Researchers Earn Grant to Test New Form of DBS to Treat Essential Tremor (MBI News)

UF Researchers Earn Grant to Test New Form of DBS to Treat Essential Tremor

University of Florida neuroscientists will test the effectiveness of a new motion-activated type of deep brain stimulation (DBS) aimed at improving treatment for patients with severe essential tremor, a neurological disorder that causes involuntary shaking and usually worsens over time.

Current DBS therapies for patients with severe essential tremor are continuous, or always-on, which can sometimes lead to undesirable side effects, including stuttering and problems with walking and balance. Under a new $3.9 million NIH grant, co-principal investigators Karim Oweiss, Ph.D., and Kelly Foote, M.D., will test responsive deep brain stimulation, or R-DBS, in a Phase I clinical trial involving approximately 10 patients over the next five years. R-DBS only turns on when it detects movements associated with essential tremor.

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