Dopamine Signaling Examination Method Promises New Insights
In a new study of human blood samples, a neuroscience research team led by Habibeh Khoshbouei, Ph.D., Pharm.D., an associate professor of neuroscience and psychiatry at UF’s College of Medicine, and graduate research assistant Adithya Gopinath demonstrated a novel approach to examine markers of dopamine signaling in peripheral immune cells.
The study, published in the Journal of Immunological Methods, describes a sensitive and reproducible approach to study the signaling of the key neurotransmitter dopamine in blood-borne human immune cells — a method that could be applied to better understand dopamine signaling both in good health and in disease. Dopamine helps regulate movement, learning, mood, and emotional responses, and this new method to examine its signaling promises to enhance and facilitate research into disorders such as Parkinson’s disease, Alzheimer’s disease and addiction.
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