Study Uncovers Insights Into Human Memory (UF Health)

Study Uncovers Insights Into Human Memory

Alzheimer’s disease is a debilitating neurodegenerative disorder affecting more than 5.5 million Americans. Now, new clinical trial results published in the New England Journal of Medicine yield a finding that could advance our understanding of human memory.

A recent trial involving 42 patients evaluated deep brain stimulation targeting the fornix, an arch-like structure connecting the hippocampus to other parts of the limbic system, with a primary aim of improving cognition in Alzheimer’s patients. Though that objective was unsuccessful, a research team led by Wissam Deeb, M.D., assistant professor of neurology at the University of Florida, analyzed a phenomenon of flashback-like cognitive experiences in nearly half of the patients occurring during initial programming of the stimulator.

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