UF Researchers Help Discover Novel Compounds That Curb Melioidosis, a Lethal Tropical Disease (UF Health Newsroom)

UF Researchers Help Discover Novel Compounds That Curb Melioidosis, a Lethal Tropical Disease

University of Florida researchers have contributed to the discovery of two molecules shown to be effective at curbing Gram-negative Burkholderia bacterial infections, which cause the highly lethal tropical disease melioidosis in humans and animals.

“The novelty of our discovery is that we found compounds that inhibit the growth of invasive Burkholderia bacteria within a host cell, and that halts its spread between cells,” said Herbert Schweizer, Ph.D., a professor of molecular genetics and microbiology in the UF College of Medicine and a member of the UF Emerging Pathogens Institute.

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