A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise and more affordable, while opening the door to entirely new ways of controlling disease.
First reported in a 2024 preprint and now formally published this week in Nature Biotechnology, the work establishes the world’s first system that uses DNA, rather than RNA, to guide CRISPR enzymes to its target, overturning the long-standing paradigm.
To understand why that matters, it helps to think of how cells work.
Read more about UF Breakthrough Could Reshape RNA Editing With World’s First DNA-Guided CRISPR.