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How Cells Power Down During Viral Attack

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Scientists Reveal Steps Cells Take to Thwart Replication

Cells have evolved ingenious ways to defend themselves from viral attack. A recent study from The Wertheim UF Scripps Institute sheds light on one of their sneakier strategies.

If there’s a prowler trying to break into one’s house, a logical reaction is to hide and call 911. Cells can do much the same. They temporarily shut down their metabolism, explains James Burke, Ph.D., an associate professor of molecular medicine at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology. But how?

In a study published in the journal Genes & Development, Burke and his team detailed the mechanics of how and when cells go dark after infection with West Nile virus.

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