UF Innovate | Accelerate client NysnoBio, with the support of Aligning Science Across Parkinson’s (ASAP) through the Michael J. Fox Foundation for Parkinson’s Research (MJFF), announces publication of studies to understand how PD mutations drive cellular phenotypes. These studies were undertaken because it’s still unclear if some PD mutations drive cellular phenotypes more than others.
A comparison of differentiated patient cells from different genetic forms of PD demonstrated that loss of Parkin is a primary driver of dopamine neuron dysfunction. This dysfunction is not present in cortical neurons, demonstrating the specific requirement for Parkin in dopamine neurons.
Read more about NysnoBio Publishes in Nature Parkinson’s Journal.
