UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
The findings, published Dec. 19 in Cell Reports Medicine, could have widespread clinical impact as a combination therapy with commonly used immunotherapy treatments like immune checkpoint inhibitors, which release the brakes on a patient’s own immune system to target their cancer.
Read more about Gut Bacteria Molecule Boosts Lung Cancer Treatment Response.