Brain Research Documentary Highlights Rumbaugh Team’s Work (The Wertheim UF Scripps Institute)
UF researcher Gavin Rumbaugh is featured in a new PBS documentary highlighting brain research with potential to advance treatments for developmental and other neurological disorders.
Myosin Therapeutics Awarded Florida Cancer Innovation Fund Grant to Support STAR-GBM Clinical Trial (Myosin News)
UF startup Myosin Therapeutics has been awarded $2 million in funding from the Florida Department of Health through the Casey DeSantis Florida Cancer Innovation Fund to support the company’s STAR-GBM Phase 1/2 clinical trial evaluating MT-125 in patients newly diagnosed with glioblastoma.
HiPerGator Supercomputer Accelerates Diabetes Drug Discovery (UF Health)
Using a blend of computer modeling, structural and cell-based studies, UF researchers have designed a group of potential diabetes drugs that reprogram insulin-resistant cells into a healthier state while limiting side effect risks of older medications.
Scientists Blaze New Path to Fighting Viral Diseases (UF Scripps)
In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by UF researchers has identified a potential new drug against the virus that causes COVID-19.
Wertheim UF Scripps Institute Research Garners $15.7 Million in New Awards (UF Scripps)
UF researchers have been awarded grants to advance projects that explore brain biology, enhance the prevention and treatment of infectious and autoimmune diseases, and combat advanced cancers.
How Cells Power Down During Viral Attack
A team of UF researchers has uncovered how cells temporarily shut down protein production during viral attack, a discovery that could shape future antiviral drug development.
Study: Gene Therapy May Block HIV Transmission During Breastfeeding
UF researchers have published in Nature a breakthrough gene therapy that delivers broadly neutralizing HIV antibodies at birth, offering long-term protection against breastfeeding transmission with a single dose.
New $7.7 Million Grant To Propel Search for Drugs for Rare Brain Disorder
Rumbaugh and a team of scientists from the institute have been awarded a five-year grant from the National Institute of Mental Health worth $7.7 million to work toward a treatment. Their goal is to create a pill that restores healthy SYNGAP1 gene production, thereby boosting neuroplasticity, or the ability of the brain to form circuits and connections.
Yikes! Scientists Discover Factor That Directs Brain’s Fear Conditioning
A team led by neuroscientists at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology has discovered a key molecular player in fear conditioning. It’s a specialized RNA with a memorable acronym, SLAMR. Their study found SLAMR must be present in adequate quantities for neurons to build the complex connections required for fear conditioning. Their research appears in the journal Nature Communications.
Targeting RNA
Disney and his team at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology in Jupiter, Florida, have discovered more than 200 unique RNA-targeting compounds. His methods and discoveries have changed minds, igniting a global race to treat incurable diseases via their RNA.