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Polycaprolactone Nanocapsules as a Tailorable Drug Delivery Platform to Specifically Targeted Human Pancreatic Beta Cells

  • Nanocapsules can be fine-tuned for drug release time scales of hours to months
  • Novel formulation that allows facile and interchangeable attachment of surface molecules, including antibodies and peptides
  • Ability to encapsulate both hydrophobic and hydrophilic drugs for controlled release
  • Provides a novel mechanism to target the islet beta cell for delivery of therapeutics
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