Autoimmune – UF Innovate https://innovate.research.ufl.edu Building business on innovation Tue, 04 Mar 2025 02:01:23 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 https://innovate.research.ufl.edu/wp-content/uploads/favicon-blue_1.png Autoimmune – UF Innovate https://innovate.research.ufl.edu 32 32 Use of Synthetic Mucus to Reduce Inflammation in Inflammatory Bowel Disease (IBD) https://innovate.research.ufl.edu/tech-bio/use-of-synthetic-mucus-to-reduce-inflammation-in-inflammatory-bowel-disease-ibd/ Tue, 04 Mar 2025 02:01:23 +0000 https://scaddev1.com/?post_type=tech-bio&p=2916
  • Improving gut barrier function and reducing intestinal permeability
  • Administer ultra-high molecular weight polymers as synthetic mucus to reduce microbes contact with epithelium
    • ]]>         Dissociated Glucocorticoids With Improved Effects in Skeletal Muscle https://innovate.research.ufl.edu/tech-bio/dissociated-glucocorticoids-with-improved-effects-in-skeletal-muscle/ Tue, 04 Mar 2025 02:01:06 +0000 https://scaddev1.com/?post_type=tech-bio&p=2914
  • Two novel glucocorticoids with reduced side effects
  • Used to treat various inflammatory and autoimmune conditions effectively
  • One of the compounds shows promise in treating cachexia
    • ]]>         REV-ERB Agonists https://innovate.research.ufl.edu/tech-bio/rev-erb-agonists/ Tue, 04 Mar 2025 02:00:46 +0000 https://scaddev1.com/?post_type=tech-bio&p=2912
  • Treatment of TH17-mediated autoimmune and inflammatory disorders
  • MS, psoriasis, IBD
  • In vivo testing in EAE and psoriasis models
  • Pre-clinical candidate selection
    • ]]>