Scientists Reveal Novel Therapeutic Approach to Combat Pathogens Like Salmonella (UF/IFAS blog)

sooyoungryu — Fri, 05 Sep 2025 15:18:45 +0000

The rise of antibiotic-resistant bacteria is a growing global health threat that is prompting research into alternative methods of fighting infection. University of Florida scientists exploring host-directed therapies, an increasingly common approach which harnesses biological processes to combat infections, have identified a promising strategy to block pathogens from hijacking key components of cellular machinery. By combining the strategy with antibiotics, they managed to nearly eliminate bacterial loads within infected cells.

The scientists, whose research was funded by the U.S. Department of Defense and the National Institutes of Health, describe their findings within a study published in mBio, a journal of the American Society for Microbiology.

Researchers Take Step Toward Creating Salmonella Vaccine

sooyoungryu — Mon, 03 Feb 2025 00:00:00 +0000

Salmonella might seem like a mild inconvenience to some, but for sensitive groups, it can prove dangerous or deadly. In fact, 26,500 people are hospitalized by the bacterial infection each year in the U.S., and 420 people die, according to the U.S. Centers for Disease Control and Prevention.

In a step toward combatting Salmonella infections, UF/IFAS microbiology researchers have published a study that they hope will lead to a vaccine against the disease.

In the U.S., about 1.35 million Salmonella infections are reported each year, according to the CDC. Salmonella infections are often caused by consuming contaminated food or water or touching infected animals or livestock or their feces, and result in severe diarrhea and even arthritis post-infection.

Salmonella – UF Innovate

Scientists Reveal Novel Therapeutic Approach to Combat Pathogens Like Salmonella (UF/IFAS blog)

Researchers Take Step Toward Creating Salmonella Vaccine