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	<title>Dong Yang &#8211; UF Innovate</title>
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	<link>https://innovate.research.ufl.edu</link>
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	<title>Dong Yang &#8211; UF Innovate</title>
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		<title>Antibody-Cancer Drug Combo Shows Promise Against Aggressive Lymphoma</title>
		<link>https://innovate.research.ufl.edu/antibody-cancer-drug-combo-shows-promise-against-aggressive-lymphoma/</link>
		
		<dc:creator><![CDATA[sooyoungryu]]></dc:creator>
		<pubDate>Thu, 03 Jul 2025 00:00:00 +0000</pubDate>
				<category><![CDATA[News Brief]]></category>
		<category><![CDATA[Tech Licensing]]></category>
		<category><![CDATA[UF Innovate]]></category>
		<category><![CDATA[ADC]]></category>
		<category><![CDATA[antibody-drug combo]]></category>
		<category><![CDATA[Ben Shen]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[Dong Yang]]></category>
		<category><![CDATA[Herbert Wertheim College of Engineering]]></category>
		<category><![CDATA[lymphomas]]></category>
		<category><![CDATA[The Wertheim UF Scripps Institute for Biomedical Innovation & Technology]]></category>
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					<description><![CDATA[A study from UF researchers shows that cancer-targeting antibodies combined with a natural compound from soil microbes form a powerful treatment against an aggressive type of blood cancer.]]></description>
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<p>Cancer-hunting antibodies coupled with a natural compound found in soil microbes proved a powerful combination against an aggressive type of blood cancer, according to a study from scientists at <a href="https://wertheim.scripps.ufl.edu/" target="_blank" rel="noreferrer noopener">The Herbert Wertheim UF Scripps Institute for Biomedical Innovation &amp; Technology</a>.</p>



<p>The cancer-killing compound, called tiancimycin, was found within a historic collection of soil microbes housed at the institute. The research team’s antibody-drug combo, or ADC, showed a striking ability to kill aggressive lymphomas while ignoring healthy, noncancerous cells in blood samples donated by cancer patients.</p>



<p>The study, funded by the National Institutes of Health, focused on diffuse large B cell lymphoma, one of the more common, and aggressive, subtypes of white blood cell cancers. The study results&nbsp;<a href="https://doi.org/10.1021/jacsau.5c00353" target="_blank" rel="noreferrer noopener">appear</a>&nbsp;July 1 in the Journal of the American Chemical Society Au.</p>



Read more about <a href="https://ufhealth.org/news/2025/antibody-cancer-drug-combo-shows-promise-against-aggressive-lymphoma"> Antibody-Cancer Drug Combo Shows Promise Against Aggressive Lymphoma.</a>



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